Tumor hypoxia causes DNA hypermethylation by reducing TET activity
DNA methylation · mouse · 99 samples
- What it is
- DNA methylationChemical marks on DNA that help switch genes on or off.
- Organism
- Mus musculus (mouse)
- Samples
- 99 samples
- Data you can get
- A processed expression table (series matrix) and the array files, from NCBI.
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE71403_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for beta-value tables or raw IDAT files among the supplementary files.
Also filed as BioProject PRJNA291096 and SRA study SRP061648. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 99 more — browse all 99 samples with per-sample file links →
- GSE243349 GPC2-Targeted CAR T Cells Engineered with NFAT-Inducible Membrane-Tethered IL15/IL21 Exhibit Enhanced Activity against Neuroblastoma 12 samples shares tet, activity
- GSE300464 TET3 Promotes Tumor Immune Evasion Through Negative Regulation of Type I Interferon Signaling 28 samples shares tet
- GSE300460 TET3 Promotes Tumor Immune Evasion Through Negative Regulation of Type I Interferon Signaling [RNA-Seq] 20 samples shares tet
- GSE278068 Nanobody-tethered transposition for dual profiling of chromatin accessibility and DNA methylation 201 samples shares tet
- GSE281919 LBR and LAP2 mediate heterochromatin tethering to the nuclear periphery to preserve genome homeostasis 111 samples shares tet
- GSE97442 Genetic and pharmacological restoration of TET2 function blocks stem cell self-renewal and progression of leukemia 80 samples shares tet
- GSE241311 TET2 regulates histone H2AK119ub and leukemogenesis through LTR RNA m5C oxidation [seq_RNA-totalRNA] 24 samples shares tet
- GSE273027 Germline TET2 variants contribute to the pathogenesis of kidney disease through impaired DNA damage repair and the activation of cytosolic nucleotide sensors 6 samples shares tet
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.