ELF5 regulates epithelial integrity independently of EHF
ChIP-seq / ATAC-seq (genome binding and open chromatin) · human · 10 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Homo sapiens (human)
- Samples
- 10 samples: 3 × T47D ELF5 ChIP-seq vs 3 × T47D siNC vs 3 × T47D siELF5Groups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE173883_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA727395. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 9 samples.
How we read this: 3 replicated groups read from 10 sample titles; they account for 9 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM5282320 T47D ELF5 ChIP-seq rep1 T47D ELF5 ChIP-seq
- GSM5282321 T47D ELF5 ChIP-seq rep2 T47D ELF5 ChIP-seq
- GSM5282322 T47D ELF5 ChIP-seq rep3 T47D ELF5 ChIP-seq
- GSM5282323 T47D_input
- GSM5282333 T47D siNC rep1 T47D siNC
- GSM5282334 T47D siNC rep2 T47D siNC
- GSM5282335 T47D siNC rep3 T47D siNC
- GSM5282336 T47D siELF5 rep1 T47D siELF5
- GSM5282337 T47D siELF5 rep2 T47D siELF5
- GSM5282338 T47D siELF5 rep3 T47D siELF5
- GSE281595 Trophoblast stem cell derivation from naive and primed hPSC enables ELF5 functional analysis (scRNAseq) 12 samples shares elf5
- GSE292059 Inflammatory Epithelial and Macrophage Pathways Underlie Residual Asthma Exacerbations in Urban Children Treated with Mepolizumab 965 samples shares epithelial
- GSE325123 The melanocytic transcriptomic state is independently associated with poor overall survival in long term follow up of patients with metastatic melanoma 272 samples shares independently
- GSE275647 Role of Cancer-Associated Fibroblasts in Prognostic Stratification of Advanced-Stage Gastric Cancer through Interacting with Endothelial and Malignant Epithelial Cells [AGC RNA-seq] 216 samples shares epithelial
- GSE271359 Identifying modulators of inflammation in an in vitro airway epithelial inflammation model using an arrayed CRISPRi screen 186 samples shares epithelial
- GSE302560 Effect of calcium oxalate microcrystals on kidney proximal tubule epithelial cell gene expression in microgravity 144 samples shares epithelial
- GSE336490 Comparative toxicogenomic profiling of human epithelial cell lines exposed to hazardous chemicals 120 samples shares epithelial
- GSE4302 Genome-Wide Profiling of Airway Epithelial Cells in Asthmatics, Smokers and Healthy Controls 118 samples shares epithelial
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.