GEO series
Phf6 mutation induces leukemogenesis through altered chromatin state in mice (RNA-Seq)
GSE198499
Mus musculus
Expression profiling by high throughput sequencing
11 samples
2026/06/01
GPL19057
Summary
To investigate the effect of PHF6 mutations in leukemogenesis, we generated Phf6R274X transgenetic(Tg) and Phf6 KO mice. Then we purified the Lineage-cKit+Sca-1+ cells from bone marrow of Phf6R274XTg, Phf6 KO and WT mice, and performed bulk RNA-seq to profile the transcriptom.
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