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Activation or maintenance of a leukemia stem cell self-renewal pathway in downstream myeloid cells

GSE20377 Mus musculus Expression profiling by array 15 samples Submitted 2010/03/15 Platform GPL8321
Summary
Activation or maintenance of a leukemia stem cell self-renewal pathway in downstream myeloid cells is an important component of AML development We generated either MLL-AF9 mediated murine leukemias that originate from committed progenitor (GMP) cells or Hoxa9/Meis1a mediated murine leukemias that originate from hematopoietic stem cells (HSC). The leukemia stem cell fraction in these two type of leukemias shared a common self-renewal pathway with normal hematopoietic stem cells. Keywords: Cell type comparison
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Also filed as BioProject PRJNA125485. Searching any of these in the dataset finder brings you back here.

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