GEO series
Histone chaperon ASF1B recruits distinct epigenetic factors in regulation of histone variant H3.3 during the fetal and adult erythropoiesis [ChIP-seq]
GSE214527
Mus musculus
Genome binding/occupancy profiling by high throughput sequencing
28 samples
2026/05/15
GPL21493
Summary
To identify the role of ASF1B in regulation of histone modification during murine erythropoiesis, H3K27ac and H3.3 ChIP-seq was performed in the WT and ASF1B KO E14.5 fetal liver and bone marrow cells. ASF1B was found bind to the promoter and potential enhancer region. Loss of ASF1B impaired H3.3 and H3K27ac enrichments during development.
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Paper (PMID 42100853) ↗
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