Convergence of aging- and rejuvenation-related epigenetic alterations on PRC2 targets [ChIP-Seq]
ChIP-seq / ATAC-seq (genome binding and open chromatin) · mouse · 17 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Mus musculus (mouse)
- Samples
- 17 samples: 6 conditions, mostly in triplicateGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Convergence of aging- and rejuvenation-related epigenetic alterations on PRC2 targetsMolecular systems biology · 2026
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE288574_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1218460 and SRA study SRP561139. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 17 samples.
How we read this: 6 replicated groups read from 17 sample titles; they account for 17 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8770163 Young tail epidermis, H3K27me3, biol rep 1 Young tail epidermis, H…
- GSM8770165 Young tail epidermis, H3K27me3, biol rep 2 Young tail epidermis, H…
- GSM8770166 Old tail epidermis, H3K27me3, biol rep 1 Old tail epidermis, H3K…
- GSM8770167 Old tail epidermis, H3K27me3, biol rep 2 Old tail epidermis, H3K…
- GSM8770168 Old tail epidermis, H3K27me3, biol rep 3 Old tail epidermis, H3K…
- GSM8770169 Young tail epidermis, INPUT, biol rep 1 Young tail epidermis, I…
- GSM8770170 Young tail epidermis, INPUT, biol rep 2 Young tail epidermis, I…
- GSM8770171 Young tail epidermis, INPUT, biol rep 3 Young tail epidermis, I…
- GSM8770172 Old tail epidermis, INPUT, biol rep 1 Old tail epidermis, INP…
- GSM8770173 Old tail epidermis, INPUT, biol rep 2 Old tail epidermis, INP…
- GSM8770174 Old tail epidermis, INPUT, biol rep 3 Old tail epidermis, INP…
- GSM9386519 Young tail epidermis, H3K9me2, biol rep 1 Young tail epidermis, H…
- GSM9386520 Young tail epidermis, H3K9me2, biol rep 2 Young tail epidermis, H…
- GSM9386521 Young tail epidermis, H3K9me2, biol rep 3 Young tail epidermis, H…
- GSM9386522 Old tail epidermis, H3K9me2, biol rep 1 Old tail epidermis, H3K…
- GSM9386523 Old tail epidermis, H3K9me2, biol rep 2 Old tail epidermis, H3K…
- GSM9386524 Old tail epidermis, H3K9me2, biol rep 3 Old tail epidermis, H3K…
- GSE289856 Convergence of aging- and rejuvenation-related epigenetic alterations on PRC2 targets 39 samples shares prc2, rejuvenation-related, convergence, alterations, epigenetic, targets, aging
- GSE289642 Noncanonical PRC2 chromatin association reveals a key role of EZHIP in intergenerational epigenetic memory transition [ChIP-Seq, Cut & Run] 107 samples shares prc2, epigenetic, chip-seq
- GSE272601 DNA glycosylases Ogg1 and Mutyh mediate gene expression of PRC2 targets important for memory formation (ChIP-Seq) 96 samples shares prc2, chip-seq, targets
- GSE270581 Chromatin distribution alterations of histone modifacations and PRC2 complex caused by Rack7 deletion in primary astrocyte [ChIP-Seq] 24 samples shares prc2, alterations, chip-seq
- GSE299940 Cortical Alterations in H3K27ac Regulation in Gene Expression Coincide Associated with Cognitive Decline and Affective Behavior in Mice During Aging: Genome-wide Epigenetic Analysis 12 samples shares alterations, epigenetic, aging
- GSE278811 EZHIP-mediated PRC2 inhibition is required to maintain H3K27me3-dependent imprinting post fertilization [ChIP-Seq] 77 samples shares prc2, chip-seq
- GSE297094 SKP1A-mediated degradation of PRC2 triggers activation of Polycomb-silenced gene [ChIP-seq 2] 73 samples shares prc2, chip-seq
- GSE249882 PRC1 and PRC2 proximal interactome in mouse embryonic stem cells [ChIP-Seq] 47 samples shares prc2, chip-seq
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.