Histone chaperon ASF1B recruits distinct epigenetic factors in regulation of histone variant H3.3 during the fetal and adult erythropoiesis
ChIP-seq / ATAC-seq (genome binding and open chromatin) · mouse · 32 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Mus musculus (mouse)
- Samples
- 32 samples: 16 conditions, mostly in duplicateGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- ASF1B promotes erythropoiesis by regulating the establishment and enrichment of H3.3 nucleosomesNucleic acids research · 2026
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE214528_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA885803 and SRA study SRP400449. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 32 samples.
How we read this: 16 replicated groups read from 32 sample titles; they account for 32 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM6610527 ASF1B WT, ATACseq, Rep1 ASF1B WT, ATACseq,
- GSM6610528 ASF1B WT, ATACseq, Rep2 ASF1B WT, ATACseq,
- GSM6610529 ASF1B KO, ATACseq, Rep1 ASF1B KO, ATACseq,
- GSM6610530 ASF1B KO, ATACseq, Rep2 ASF1B KO, ATACseq,
- GSM6610531 WT, input-1 WT, input
- GSM6610532 WT, input-2 WT, input
- GSM6610533 WT, H3K27acIP-1 WT, H3K27acIP
- GSM6610534 WT, H3K27acIP-2 WT, H3K27acIP
- GSM6610535 WT, H3.3IP-1 WT, H3.3IP
- GSM6610536 WT, H3.3IP-2 WT, H3.3IP
- GSM6610537 WT, HAIP-1 WT, HAIP
- GSM6610538 WT, HAIP-2 WT, HAIP
- GSM6610539 KO, input-1 KO, input
- GSM6610540 KO, input-2 KO, input
- GSM6610541 KO, H3K27acIP-1 KO, H3K27acIP
- GSM6610542 KO, H3K27acIP-2 KO, H3K27acIP
- GSM6610543 KO, H3.3IP-1 KO, H3.3IP
- GSM6610544 KO, H3.3IP-2 KO, H3.3IP
- GSM6610545 BMWT, input-1 BMWT, input
- GSM6610546 BMWT, input-2 BMWT, input
- GSM6610547 BMWT, H3K27acIP-1 BMWT, H3K27acIP
- GSM6610548 BMWT, H3K27acIP-2 BMWT, H3K27acIP
- GSM6610549 BMWT, H3.3IP-1 BMWT, H3.3IP
- GSM6610550 BMWT, H3.3IP-2 BMWT, H3.3IP
- GSM6610551 BMWT, HAIP-1 BMWT, HAIP
- GSM6610552 BMWT, HAIP-2 BMWT, HAIP
- GSM6610553 BMKO, input-1 BMKO, input
- GSM6610554 BMKO, input-2 BMKO, input
- GSM6610555 BMKO, H3K27acIP-1 BMKO, H3K27acIP
- GSM6610556 BMKO, H3K27acIP-2 BMKO, H3K27acIP
- GSM6610557 BMKO, H3.3IP-1 BMKO, H3.3IP
- GSM6610558 BMKO, H3.3IP-2 BMKO, H3.3IP
- GSE235109 Ensembles of genome-coverage single-cell histone modifications reveal epigenetic lineages during mouse preimplantation development 47 samples shares epigenetic, histone
- GSE283727 Histone 3 lysine 36 methylation shapes an epigenetic landscape in intestinal stem cell to orchestrate lipid metabolism and prevent cell senescence [CUT&Tag] 12 samples shares epigenetic, histone
- GSE276632 Reciprocal genetic screens identify epigenetics factors controlling epidermal cell activation. 262 samples shares epigenetic, factors
- GSE276628 Reciprocal genetic screens identify epigenetics factors controlling epidermal cell activation. [RNAseq_MiniBulk] 41 samples shares epigenetic, factors
- GSE157232 The CD8+ T cell tolerance checkpoint triggers a transcriptionally and epigenetically distinct differentiation state defined by protein translation defects 30 samples shares epigenetic, distinct
- GSE308116 Epigenetic modification, as a distinctive therapeutic molecule for Parkinson’s disease gene therapy. 17 samples shares epigenetic, distinct
- GSE244496 Establishment of nuclear organization in mouse embryos is regulated by multiple and redundant epigenetic pathways. 183 samples shares epigenetic
- GSE289642 Noncanonical PRC2 chromatin association reveals a key role of EZHIP in intergenerational epigenetic memory transition [ChIP-Seq, Cut & Run] 107 samples shares epigenetic
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.