GEO series
Establishment of nuclear organization in mouse embryos is regulated by multiple and redundant epigenetic pathways.
GSE244496
Mus musculus
Genome binding/occupancy profiling by high throughput sequencing
183 samples
2025/04/10
GPL21103
Summary
How the pillars of nuclear organization are first established during development is not fully understood at the molecular level. Here, we investigated one of the foundations of nuclear organization, the lamina-associated domains (LADs) and undertook a screening to identify the molecular pathways regulating LAD establishment in vivo, in early mouse embryos.
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Paper (PMID 40273908) ↗
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