Single-cell RNA sequencing of peripheral blood mononuclear cell of human osteosarcoma
Single-cell RNA-seq · human · 3 samples
- What it is
- Single-cell RNA-seqGene activity measured in thousands of individual cells, so cell types can be told apart.
- Organism
- Homo sapiens (human)
- Topic
- OsteosarcomaThis series is part of our curated briefing on it.
- Samples
- 3 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE216280_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Single-cell studies usually ship their counts as 10x files (matrix.mtx, barcodes.tsv, features.tsv), an .h5 file, or an .rds / .h5ad object that Seurat or Scanpy can open. Look for those among the supplementary files.
Also filed as BioProject PRJNA892924 and SRA study SRP403899. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 3 more — browse all 3 samples with per-sample file links →
- GSE162454 Single-cell RNA sequencing of human osteosarcoma 6 samples same disease briefing · shares osteosarcoma, single-cell
- GSE250015 Exploring the impact of PDGFD in osteosarcoma metastasis through single-cell sequencing analysis 2 samples same disease briefing · shares osteosarcoma, single-cell
- GSE318840 Single-Cell Fixed RNA Profiling of Osteosarcoma Evolution Reveals a Coordinated Multi-cellular Network Driving Metastasis 8 samples same disease briefing · shares osteosarcoma, single-cell
- GSE237070 Single-cell RNA sequencing of human various osteosarcoma tissues 9 samples same disease briefing · shares osteosarcoma, single-cell
- GSE152048 Single cell analysis of osteosarcoma tissues 76 samples same disease briefing · shares osteosarcoma
- GSE245562 RNA sequencing to determine gene expression changes in SQLE knockdown osteosarcoma cells 6 samples same disease briefing · shares osteosarcoma
- GSE250492 Effect of over expression of MED13 IDR in human osteosarcoma U2OS cell line 6 samples same disease briefing · shares osteosarcoma
- GSE324043 Celastrol induces autophagy and apoptosis of human osteosarcoma cells via downregulation PI3K/Akt/mTOR signaling pathway 6 samples same disease briefing · shares osteosarcoma
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.