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Celastrol induces autophagy and apoptosis of human osteosarcoma cells via downregulation PI3K/Akt/mTOR signaling pathway

GSE324043 Homo sapiens Expression profiling by high throughput sequencing 6 samples Submitted 2026/03/11 Platform GPL24676
Summary
Celastrol, a terpenoid compound isolated from the plant Tripterygium wilfordii (Thunder God Vine), has been shown to have powerful anti-tumor effects against various developing cancers. Osteosarcoma is the most common primary bone malignancy in children and adolescents, and its long-term survival has remained stagnant over the past few decades.
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Direct links to NCBI, no account and no request form: the whole study as GSE324043_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 6 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1433270 and SRA study SRP681615. Searching any of these in the dataset finder brings you back here.

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