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FBXO45, a new guardian of the genome

GSE218662 Mus musculus Expression profiling by high throughput sequencing 4 samples Submitted 2024/12/01 Platform GPL21103
Summary
Conditional knockout of Fbxo45 in alveolar epithelial type II cells (AT2) in mice (cKO) resulted in spontaneous lung adenocarcinoma. To investigate why deletion of Fbxo45 in AT2 leads to lung adenocarcinoma. We isolated primary AT2 cells from 6-month-old WT, cKO mice for high-throughput RNA-sequencing analysis. (WT=2, cKO=2)
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Also filed as BioProject PRJNA904773 and SRA study SRP409516. Searching any of these in the dataset finder brings you back here.

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