GEO series
Transcriptomic and epigenetic investigation of Zika virus (ZIKV) and Dengue virus (DENV) infection in human monocyte-derived dendritic cells
GSE220842
Homo sapiens
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing
45 samples
2025/02/22
GPL18573GPL20301GPL24676
Summary
Dendritic cells are key targets for ZIKV and DENV infection. To identify host pathways manipulated by ZIKV and DENV in dendritic cells, we developed a system that enables characterization of genome-wide transcriptional and epigenetic changes in virus-infected and neighboring (bystander), uninfected primary human dendritic cells.
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Paper (PMID 40133263) ↗
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