Eosinophils in Lung Allograft
RNA-seq (gene expression) · mouse · 20 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 20 samples: 5 × Resting_Lung vs 5 × Day 7 vs 5 × Day 30Groups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Eosinophils restrain humoral alloimmunity after lung transplantationJCI insight · 2024
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE223352_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA925858 and SRA study SRP418443. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 15 samples.
How we read this: 3 replicated groups read from 20 sample titles; they account for 15 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM6946010 Resting_Lung 1 Resting_Lung
- GSM6946011 Resting_Lung 2 Resting_Lung
- GSM6946012 Resting_Lung 3 Resting_Lung
- GSM6946013 Resting_Lung 4 Resting_Lung
- GSM6946014 Resting_Lung 5 Resting_Lung
- GSM6946015 Day 7_1 Day 7
- GSM6946016 Day 7_2 Day 7
- GSM6946017 Day 7_3 Day 7
- GSM6946018 Day 7_4 Day 7
- GSM6946019 Day 7_5 Day 7
- GSM6946020 Day 30_1 Day 30
- GSM6946021 Day 30_2 Day 30
- GSM6946022 Day 30_3 Day 30
- GSM6946023 Day 30_4 Day 30
- GSM6946024 Day 30_5 Day 30
- GSM8763393 Day7_1 no CSB
- GSM8763394 Day7_2 no CSB
- GSM8763395 Day 7_3 no CSB
- GSM8763396 Day 7_4 no CSB
- GSM8763397 Day 7_5 no CSB
- GSE251931 Maintenance of tolerance after lung transplantation is dependent on the preservation of allograft tissue-resident Foxp3+ T cells 15 samples shares allograft, lung
- GSE263892 Single-cell analysis reveals Mycobacterium tuberculosis ESX-1-mediated accumulation of permissive macrophages in infected mouse lungs 6078 samples shares lung
- GSE319684 Timecourse of FACS sorted Ly6C+ monocytes, tissue resident alveolar macrophages (trAMs), monocyte derived alveolar macrophages (bmAMs) and epithelial cells from SARS-CoV-2 (maVie16) vs. IAV (PR8) infected mouse lungs 176 samples shares lung
- GSE287098 Influenza virus-induced type I interferons disrupt alveolar epithelial repair and tight junction integrity in the developing lung 96 samples shares lung
- GSE280003 Gpnmb and Spp1 mark a conserved macrophage injury response masking fibrosis-specific programming in the lung 81 samples shares lung
- GSE317602 Lung gene expression in WT and estrogen receptor alpha and beta knockout mice exposed to house dust mites 72 samples shares lung
- GSE253735 Loss of skeletal muscle Bmal1 +/- Exercise Training [Mouse liver, heart, inguinal white adipose and lung tissues 64 samples shares lung
- GSE303739 Organoid modeling of lung branching morphogenesis and epithelial lineage specification 56 samples shares lung
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.