Brain changes in responses of mice to intracerebral hemorrhage at the acute stages
RNA-seq (gene expression) · mouse · 12 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 12 samples: 6 × ICH vs 6 × shamGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE225651_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA936883 and SRA study SRP423593. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 12 samples.
How we read this: 2 replicated groups read from 12 sample titles; they account for 12 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM7053823 ICH_1 ICH
- GSM7053824 ICH_2 ICH
- GSM7053825 ICH_3 ICH
- GSM7053826 ICH_4 ICH
- GSM7053827 ICH_5 ICH
- GSM7053828 ICH_6 ICH
- GSM7053829 sham_1 sham
- GSM7053830 sham_2 sham
- GSM7053831 sham_3 sham
- GSM7053832 sham_4 sham
- GSM7053833 sham_5 sham
- GSM7053834 sham_6 sham
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- GSE237260 Transcriptome Analysis Reveals Gene Expression Changes in a mouse Model of Hyperoxia-induced acute lung injury 12 samples shares changes, acute
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- GSE295108 Fatty acid-binding protein 4 drives neuroinflammation after intracerebral hemorrhage 12 samples shares intracerebral, hemorrhage
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- GSE326616 Aldosterone-induced gene expression changes in the brain 12 samples shares changes, brain
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Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.