Aldosterone-induced gene expression changes in the brain
ChIP-seq / ATAC-seq (genome binding and open chromatin) · mouse · 12 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Mus musculus (mouse)
- Samples
- 12 samples: 10 distinct titles, 2 of them repeatedGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE326616_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1446033 and SRA study SRP687817. Searching any of these in the dataset finder brings you back here.
How we read this: Read from 12 sample titles: 10 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM9631010 Vehicle treated DVC, female, Epi Multiome chemistry, GEX, replicate 1
- GSM9631011 Vehicle treated DVC, female, Epi Multiome chemistry, ATAC, replicate 1
- GSM9631012 Vehicle treated DVC, male, Epi Multiome chemistry, GEX, replicate 1
- GSM9631013 Vehicle treated DVC, male, Epi Multiome chemistry, ATAC, replicate 1
- GSM9631014 Aldosterone treated DVC, female, Epi Multiome chemistry, GEX, replicate 1
- GSM9631015 Aldosterone treated DVC, female, Epi Multiome chemistry, ATAC, replicate 1
- GSM9631016 Aldosterone treated DVC, male, Epi Multiome chemistry, GEX, replicate 1
- GSM9631017 Aldosterone treated DVC, male, Epi Multiome chemistry, ATAC, replicate 1
- GSM9631018 Vehicle-treated DVC, GEM-X chemistry, replicate 2
- GSM9631019 Aldosterone-treated DVC, GEM-X chemistry, replicate 2
- GSM9631020 Vehicle-treated DVC, GEM-X chemistry, replicate 3
- GSM9631021 Aldosterone-treated DVC, GEM-X chemistry, replicate 3
- GSE233837 Comprehensive transcriptome analysis reveals altered mRNA splicing and post-transcriptional changes in the aged mouse brain 24 samples shares changes, brain
- GSE225651 Brain changes in responses of mice to intracerebral hemorrhage at the acute stages 12 samples shares changes, brain
- GSE272888 Dynamic transcriptional and epigenetic changes define postnatal tendon growth 54 samples shares changes
- GSE293881 Single cell 10X Genomics Multiome Analysis of H3.3K4M Mutant Brain Samples 32 samples shares brain
- GSE290224 Intermittent Fasting Reprograms Chromatin Accessibility to Modulate Gene Expression in Brain and Muscle 96 samples shares brain
- GSE318815 Differential sex-dependent responses of circulating steroid hormones and cortical gene expression in a preclinical traumatic brain injury model 88 samples shares brain
- GSE302808 Depletion of Peripheral Monocytes Alters Long-Term Gene Expression in Microglia in a Murine Model of Traumatic Brain Injury 84 samples shares brain
- GSE310244 Dynamic Resilience: Stress Phenotypes and Their Impact on Opioid-Taking Behavior, Brain Activity, and Gene Expression 68 samples shares brain
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.