Splicing changes in gastrocnemius muscle from 3-month-old HSALR mice
RNA-seq (gene expression) · mouse · 16 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 16 samples: 5 × HSA_CTRL__S vs 5 × HSA_AICAR__S vs 3 × FVB_AICAR__S vs 3 × FVB_CTRL__SGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- CaMKIIβ deregulation contributes to neuromuscular junction destabilization in Myotonic Dystrophy type ISkeletal muscle · 2024
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE226676_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA941217 and SRA study SRP425788. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 16 samples.
How we read this: 4 replicated groups read from 16 sample titles; they account for 16 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM7081406 HSA_CTRL__S452 HSA_CTRL__S
- GSM7081407 FVB_AICAR__S447 FVB_AICAR__S
- GSM7081408 HSA_AICAR__S460 HSA_AICAR__S
- GSM7081409 HSA_AICAR__S463 HSA_AICAR__S
- GSM7081410 HSA_AICAR__S455 HSA_AICAR__S
- GSM7081411 FVB_CTRL__S446 FVB_CTRL__S
- GSM7081412 HSA_AICAR__S454 HSA_AICAR__S
- GSM7081413 FVB_AICAR__S449 FVB_AICAR__S
- GSM7081414 HSA_CTRL__S451 HSA_CTRL__S
- GSM7081415 HSA_AICAR__S462 HSA_AICAR__S
- GSM7081416 HSA_CTRL__S453 HSA_CTRL__S
- GSM7081417 FVB_CTRL__S445 FVB_CTRL__S
- GSM7081418 FVB_CTRL__S450 FVB_CTRL__S
- GSM7081419 HSA_CTRL__S459 HSA_CTRL__S
- GSM7081420 FVB_AICAR__S448 FVB_AICAR__S
- GSM7081421 HSA_CTRL__S458 HSA_CTRL__S
- GSE311069 Elimination of myotonia improves myopathy in a muscleblind knockout model of myotonic dystrophy: Deep RNAseq of quadriceps muscle to assess myotonia dependent changes in transcript expression and splicing. 16 samples shares splicing, changes, muscle
- GSE266882 Analysis of gastrocnemius muscle transcriptome from chow fed control and skeletal muscle HuR knockout mice with and without voluntary wheel running 56 samples shares gastrocnemius, muscle
- GSE325832 RNA-seq analysis of skeletal muscle from control (Cre) and Terf2 knockout (KO) mice in gastrocnemius-plantaris-soleus (GPS) and tibialis anterior (TA) 35 samples shares gastrocnemius, muscle
- GSE286904 Persistent large-scale changes in alternative splicing in prefrontal cortical neuron types following psychedelic exposure 118 samples shares splicing, changes
- GSE263105 Effect of muscle-specific Pex5 depletion on gene expression in gastrocnemius muscle in 18 months-old mice 14 samples shares gastrocnemius, muscle
- GSE263104 Effect of muscle-specific Pex5 depletion on gene expression in gastrocnemius muscle in 9 months-old mice 13 samples shares gastrocnemius, muscle
- GSE249868 Effect of Calcipotriol on gene expression in gastrocnemius muscle of SKO mice. 12 samples shares gastrocnemius, muscle
- GSE282096 Diminished transcriptional activity and splicing changes drive gene length-biased rewiring in the aging transcriptome (RNA-Seq) 94 samples shares splicing, changes
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.