Effect of Calcipotriol on gene expression in gastrocnemius muscle of SKO mice.
RNA-seq (gene expression) · mouse · 12 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 12 samples: 3 × SKO_Cal_biol vs 3 × SKO_veh_biol vs 3 × SWT_Cal_biol vs 3 × SWT_veh_biolGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- The Effects of Vitamin D on Muscle Strength Are Influenced by Testosterone LevelsJournal of cachexia, sarcopenia and muscle · 2025
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE249868_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1051058 and SRA study SRP477350. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 12 samples.
How we read this: 4 replicated groups read from 12 sample titles; they account for 12 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM7966180 SKO_Cal_biol rep 1 SKO_Cal_biol
- GSM7966181 SKO_Cal_biol rep 2 SKO_Cal_biol
- GSM7966182 SKO_Cal_biol rep 3 SKO_Cal_biol
- GSM7966183 SKO_veh_biol rep 1 SKO_veh_biol
- GSM7966184 SKO_veh_biol rep 2 SKO_veh_biol
- GSM7966185 SKO_veh_biol rep 3 SKO_veh_biol
- GSM7966186 SWT_Cal_biol rep 1 SWT_Cal_biol
- GSM7966187 SWT_Cal_biol rep 2 SWT_Cal_biol
- GSM7966188 SWT_Cal_biol rep 3 SWT_Cal_biol
- GSM7966189 SWT_veh_biol rep 1 SWT_veh_biol
- GSM7966190 SWT_veh_biol rep 2 SWT_veh_biol
- GSM7966191 SWT_veh_biol rep 3 SWT_veh_biol
- GSE263106 Effect of muscle-specific Pex5 depletion on gene expression in gastrocnemius muscle 36 samples shares gastrocnemius, muscle
- GSE266882 Analysis of gastrocnemius muscle transcriptome from chow fed control and skeletal muscle HuR knockout mice with and without voluntary wheel running 56 samples shares gastrocnemius, muscle
- GSE325832 RNA-seq analysis of skeletal muscle from control (Cre) and Terf2 knockout (KO) mice in gastrocnemius-plantaris-soleus (GPS) and tibialis anterior (TA) 35 samples shares gastrocnemius, muscle
- GSE297388 Spatial transcriptomics and scRNA-sequencing on gastrocnemius muscle form B6-mdx and D2-mdx mice 8 samples shares gastrocnemius, muscle
- GSE186648 Skeletal muscle mRNA expression in 25 mice with or without genetic defects of mitochondrial fatty acid oxidation (Acadl and Acadvl knockout) using RNA sequencing. 25 samples shares muscle
- GSE287832 Effect of aging on gene expression in the skeletal muscle 18 samples shares muscle
- GSE290224 Intermittent Fasting Reprograms Chromatin Accessibility to Modulate Gene Expression in Brain and Muscle 96 samples shares muscle
- GSE237747 Transcriptomic profiling across 20 CC-RIX genetic backgrounds with and without high-fat high-sugar (HFHS) diet, and with and without metformin [skeletal muscle] 703 samples shares muscle
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.