Effect of muscle-specific Pex5 depletion on gene expression in gastrocnemius muscle in 18 months-old mice
RNA-seq (gene expression) · mouse · 14 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 14 samples: 7 × gastrocnemius muscle from 18 months-old control mice, WT vs 7 × gastrocnemius muscle from 18 months-old Pex-KO mice, KOGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Alterations in peroxisome-mitochondria interplay in skeletal muscle accelerate muscle dysfunctionNature communications · 2025
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE263105_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1095857 and SRA study SRP499508. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 14 samples.
How we read this: 2 replicated groups read from 14 sample titles; they account for 14 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8185821 gastrocnemius muscle from 18 months-old control mice, WT_068 gastrocnemius muscle fr…
- GSM8185822 gastrocnemius muscle from 18 months-old control mice, WT_077 gastrocnemius muscle fr…
- GSM8185823 gastrocnemius muscle from 18 months-old control mice, WT_078 gastrocnemius muscle fr…
- GSM8185824 gastrocnemius muscle from 18 months-old control mice, WT_102 gastrocnemius muscle fr…
- GSM8185825 gastrocnemius muscle from 18 months-old control mice, WT_104 gastrocnemius muscle fr…
- GSM8185826 gastrocnemius muscle from 18 months-old control mice, WT_106 gastrocnemius muscle fr…
- GSM8185827 gastrocnemius muscle from 18 months-old control mice, WT_107 gastrocnemius muscle fr…
- GSM8185828 gastrocnemius muscle from 18 months-old Pex-KO mice, KO_054 gastrocnemius muscle fr…
- GSM8185829 gastrocnemius muscle from 18 months-old Pex-KO mice, KO_063 gastrocnemius muscle fr…
- GSM8185830 gastrocnemius muscle from 18 months-old Pex-KO mice, KO_070 gastrocnemius muscle fr…
- GSM8185831 gastrocnemius muscle from 18 months-old Pex-KO mice, KO_071 gastrocnemius muscle fr…
- GSM8185832 gastrocnemius muscle from 18 months-old Pex-KO mice, KO_072 gastrocnemius muscle fr…
- GSM8185833 gastrocnemius muscle from 18 months-old Pex-KO mice, KO_079 gastrocnemius muscle fr…
- GSM8185834 gastrocnemius muscle from 18 months-old Pex-KO mice, KO_007 gastrocnemius muscle fr…
- GSE263104 Effect of muscle-specific Pex5 depletion on gene expression in gastrocnemius muscle in 9 months-old mice 13 samples shares pex5, muscle-specific, gastrocnemius, months-old, depletion, muscle
- GSE263103 Effect of muscle-specific Pex5 depletion on gene expression in gastrocnemius muscle in 3 months-old mice 9 samples shares pex5, muscle-specific, gastrocnemius, months-old, depletion, muscle
- GSE263106 Effect of muscle-specific Pex5 depletion on gene expression in gastrocnemius muscle 36 samples shares pex5, muscle-specific, gastrocnemius, depletion, muscle
- GSE249868 Effect of Calcipotriol on gene expression in gastrocnemius muscle of SKO mice. 12 samples shares gastrocnemius, muscle
- GSE232957 Muscle-specific rescue of Bmal1 impacts survival and health span of the Bmal1-KO mouse 72 samples shares muscle-specific, muscle
- GSE266882 Analysis of gastrocnemius muscle transcriptome from chow fed control and skeletal muscle HuR knockout mice with and without voluntary wheel running 56 samples shares gastrocnemius, muscle
- GSE325832 RNA-seq analysis of skeletal muscle from control (Cre) and Terf2 knockout (KO) mice in gastrocnemius-plantaris-soleus (GPS) and tibialis anterior (TA) 35 samples shares gastrocnemius, muscle
- GSE226676 Splicing changes in gastrocnemius muscle from 3-month-old HSALR mice 16 samples shares gastrocnemius, muscle
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.