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Selective translation of nuclear mitochondrial respiratory proteins reprograms succinate metabolism in AML development and chemoresistance.[ChIP-seq]

GSE226913 Mus musculus Genome binding/occupancy profiling by high throughput sequencing 20 samples 2024/09/24 GPL24247
Summary
Here we identify a novel RAS-responsive element binding protein 1 short isoform, RREB1S, as a key in governing mitochondrial complex II translation to promote stemness and drug resistance of cancer stem cells of acute myeloid leukemia
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