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Ketolysis is a metabolic driver of CD8+ T cell effector function through histone acetylation [ChIP-seq]

GSE229358 Mus musculus Genome binding/occupancy profiling by high throughput sequencing 8 samples Submitted 2025/07/09 Platform GPL24247
Summary
Investigating the effects of Bdh1 deletion on acetylation of lysine 27 on histone 3 (H3K27ac) in CD8+ T cells 24 h post-activation with anti-CD3 and anti-CD28 antibodies
Published in
Ketolysis drives CD8(+) T cell effector function through effects on histone acetylation
Luda KM, Longo J, Kitchen-Goosen SM et al. · Immunity 2023 · PMID 37516105 · doi:10.1016/j.immuni.2023.07.002
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Also filed as BioProject PRJNA954063 and SRA study SRP431872. Searching any of these in the dataset finder brings you back here.

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