← BioTransfer GEO Dataset Finder
GEO series

Gene expression profiling of ST-HSCs and MPP2 cells conditionally expressing MLL-ENL by RNA-seq

GSE229484 Mus musculus Expression profiling by high throughput sequencing 4 samples Submitted 2024/05/08 Platform GPL28457
Summary
To investigate the molecular mechanism of leukemic transformation by MLL-ENL in HSCs and immature progenitors, we preliminarily performed comprehensive gene expression profiling of ST-HSCs and MPP2 cells by RNA-seq using a mouse model enabling to conditionally express MLL-ENL at an endogenous-like expression level.
Published in
Bahcc1 is critical for the aberrant epigenetic program in a mouse model of MLL-ENL-mediated leukemia
Nakamura A, Masuya M, Shinmei M et al. · Blood advances 2024 · PMID 38452334 · doi:10.1182/bloodadvances.2023011320
This dataset
Download

Direct links to NCBI, no account and no request form: the whole study as GSE229484_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 4 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA954738 and SRA study SRP432178. Searching any of these in the dataset finder brings you back here.

Samples in this study

The sample list for this study is not cached yet. Press Sort into groups and it will be fetched from NCBI.

+ 4 more — browse all 4 samples with per-sample file links →

Similar datasets

Search all mouse RNA-seq datasets in GEO →

Share this dataset

Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.