RNA-seq of the 4 stages of maturation of eosinophils in the murine bone marrow in the steady state and in Interleukin-33- induced eosinophilia.
RNA-seq (gene expression) · mouse · 24 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 24 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Single-cell proteomics and transcriptomics capture eosinophil development and identify the role of IL-5 in their lineage transit amplificationImmunity · 2024
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE229824_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA956271 and SRA study SRP432867. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 24 more — browse all 24 samples with per-sample file links →
- GSE248712 Study of the impact of Anti-IL5 neutralizing antibodies on bone marrow eosinophil maturation stages during IL-33 induced eosinophilia. 22 samples shares eosinophilia, maturation, induced, stages, marrow
- GSE278867 GFI1-FOXO1 axis regulate NK cell maturation and function [RNA-seq] 74 samples shares maturation, rna-seq
- GSE240857 Hmgb2 improves astrocyte to neuron conversion by increasing the chromatin accessibility of genes associated with neuronal maturation in a proneuronal factor-dependent manner[RNA-Seq] 29 samples shares maturation, rna-seq
- GSE334547 ACKR2 aids the regulation of bone marrow eosinophils to promote monocyte differentiation and anti-bacterial immunity 26 samples shares eosinophils, marrow
- GSE286908 Bacterial skin infection imprints bone marrow eosinophils to promote allergic skin-lung crosstalk [Quant_seq] 24 samples shares eosinophils, marrow
- GSE270648 The unfolded protein sensor IRE1 is essential for homeostatic dendritic cell maturation [RNA-seq] 19 samples shares maturation, rna-seq
- GSE260706 Alterations in cellular metabolic pathway and epithelial cell maturation induced by MYO5B defects are partially reversible by LPAR5 activation 16 samples shares maturation, induced
- GSE224703 Bulk transcriptomic profiling of eosinophils from skin and bone marrow during atopic dermatitis 16 samples shares eosinophils, marrow
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.