Bulk transcriptomic profiling of eosinophils from skin and bone marrow during atopic dermatitis
RNA-seq (gene expression) · mouse · 16 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 16 samples: 4 × BM_mouse vs 4 × H_mouse vs 4 × C_mouse vs 4 × L_mouseGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Guided monocyte fate to FRβ/CD163(+) S1 macrophage antagonises atopic dermatitis via fibroblastic matrices in mouse hypodermisCellular and molecular life sciences : CMLS · 2024
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE224703_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA932235 and SRA study SRP421318. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 16 samples.
How we read this: 4 replicated groups read from 16 sample titles; they account for 16 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM7029812 BM_mouse1 BM_mouse
- GSM7029813 H_mouse1 H_mouse
- GSM7029814 C_mouse1 C_mouse
- GSM7029815 L_mouse1 L_mouse
- GSM7029816 BM_mouse2 BM_mouse
- GSM7029817 H_mouse2 H_mouse
- GSM7029818 C_mouse2 C_mouse
- GSM7029819 L_mouse2 L_mouse
- GSM7029820 BM_mouse3 BM_mouse
- GSM7029821 H_mouse3 H_mouse
- GSM7029822 C_mouse3 C_mouse
- GSM7029823 L_mouse3 L_mouse
- GSM7029824 BM_mouse4 BM_mouse
- GSM7029825 H_mouse4 H_mouse
- GSM7029826 C_mouse4 C_mouse
- GSM7029827 L_mouse4 L_mouse
- GSE314281 bulkRNA-seq LSKs CMPs MEPs GMPs from bone marrow and spleen 32 samples shares marrow, bulk, bone
- GSE334547 ACKR2 aids the regulation of bone marrow eosinophils to promote monocyte differentiation and anti-bacterial immunity 26 samples shares eosinophils, marrow, bone
- GSE331360 Bulk RNA sequencing of bone marrow-derived macrophages from WT and Ch25h-KO mice under different treatment conditions 24 samples shares marrow, bulk, bone
- GSE262396 Mitochondria-enriched hematopoietic stem cells exhibit elevated self-renewal capabilities, thriving within the context of aged bone marrow [bulk RNA-seq] 24 samples shares marrow, bulk, bone
- GSE313387 Brain-Engrafted Monocyte-derived Macrophages from Blood and Skull-Bone Marrow Exhibit Distinct Properties [bulkRNA_isolatedBrainParenchymalMacrophages] 18 samples shares marrow, bulk, bone
- GSE293533 Bulk RNA sequencing of bone marrow CD8+ T cells in BMF mice treated with or without baricitinib at different time points 16 samples shares marrow, bulk, bone
- GSE262128 Bulk RNA-seq of mouse bone marrow derived macrophages co-cultured with platelets 16 samples shares marrow, bulk, bone
- GSE189370 Bulk RNA sequencing and analysis of sorted Common Lymphoid Progenitor (CLP) cells from WT, Notch1+/-, and Notch1+/ΔTAD adult mouse bone marrow 13 samples shares marrow, bulk, bone
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.