GEO series
Bulk transcriptomic profiling of eosinophils from skin and bone marrow during atopic dermatitis
GSE224703
Mus musculus
Expression profiling by high throughput sequencing
16 samples
2024/12/25
GPL30172
Summary
Atopic dermatitis was induced on dorsal skin of 7-10 week-old C57BL/6 female mice by bi- or tri-daily MC903 treatment. On day 8, viable mouse eosinophils (CD45+F4/80+SiglecF+) were sorted from skin regions of healthy or vehicle/treated atopic dermatitis or femur/tibia-derived bone marrow by FACS. Samples were paired within individual mice (4 mice each). RNA from 500 cells were isolated and profile for transcriptome by sequencing.
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Paper (PMID 39720957) ↗
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