Sciatic nerve crush regulation of ribosome-associated RNA in DRG neurons
RNA-seq (gene expression) · mouse · 12 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 12 samples: 3 × IP Naïve vs 3 × IP Injury vs 3 × Input Naïve vs 3 × Input InjuryGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Repeat-element RNAs integrate a neuronal growth circuitCell · 2025
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE230722_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA962455 and SRA study SRP434831. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 12 samples.
How we read this: 4 replicated groups read from 12 sample titles; they account for 12 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM7233086 1_1: IP Naïve replicate 1 IP Naïve
- GSM7233087 1_2: IP Naïve replicate 2 IP Naïve
- GSM7233088 1_3: IP Naïve replicate 3 IP Naïve
- GSM7233089 2_1: IP Injury replicate 1 IP Injury
- GSM7233090 2_2: IP Injury replicate 2 IP Injury
- GSM7233091 2_3: IP Injury replicate 3 IP Injury
- GSM7233092 3_1: Input Naïve replicate 1 Input Naïve
- GSM7233093 3_2: Input Naïve replicate 2 Input Naïve
- GSM7233094 3_3: Input Naïve replicate 3 Input Naïve
- GSM7233095 4_1: Input Injury replicate 1 Input Injury
- GSM7233096 4_2: Input Injury replicate 2 Input Injury
- GSM7233097 4_3: Input Injury replicate 3 Input Injury
- GSE249687 Three-dimensional chromatin architecture in DRG neurons following sciatic nerve injury in WT and Rad21 KO mice. 52 samples shares drg, sciatic, neurons, nerve
- GSE301321 DRG tissue CSDE1-IP sequencing using sciatic nerve injured and uninjured mice. 12 samples shares drg, sciatic, nerve
- GSE301319 DRG tissue RiboTag and bulk RNA sequencing using sciatic nerve injured and uninjured mice. 12 samples shares drg, sciatic, nerve
- GSE230720 Sciatic nerve crush upregulation of B2-SINE expression at specific genomic loci 16 samples shares sciatic, nerve, crush
- GSE243308 Aryl hydrocarbon receptor restricts axon regeneration of DRG neurons in response to injury 26 samples shares drg, neurons
- GSE302022 Biological processes in Nav1.8-posistive DRG neurons after PTX treatment (the long model) in control (LTβR-fl/fl) and Na1.8-cre/LRβR-fl/fl mice 16 samples shares drg, neurons
- GSE262153 Targeting GI-SINE (Growth inducing B2-SINE) RNA in DRG neurons by Antisense Oligonucleotides (ASO) 12 samples shares drg, neurons
- GSE252398 Genome wide map of Runx3, Brn3a, Islet1 binding, chromatin accessibility (ATAC) and Histone H3 acetylated on lysine 27 (H3K27Ac) during early development of DRG TrkC neurons 26 samples shares drg, neurons
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.