GEO series
Effect of FOSL1 and HDAC2 knockdown on gene expression in cancer cell lines
GSE230729
Homo sapiens
Expression profiling by high throughput sequencing
12 samples
2024/04/27
GPL20795
Summary
We identifled FOSL1 and HDAC2 as master regulators of cancer cell metabolism. To validate their function, we knockdown FOSL1 in pancreatic adenocarcinoma cell line PANC-1 and HDAC2 in lung adenocarcinoma cell line H1299, respectively. Then RNA-seq was performed to investigate the alterations of metabolic genes.
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Paper (PMID 39393173) ↗
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