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Oleanolic acid inhibits the development of breast cancer by regulating lactic acid bacteria and the Cytokinecytokine receptor interaction pathway

GSE231570 Mus musculus Expression profiling by high throughput sequencing 6 samples Submitted 2024/03/13 Platform GPL24247
Summary
It was found that after OA treatment, compared with the CK group, the abundance of lactic acid bacteria in the intestinal flora of mice in the OA group increased, and the increase in the abundance of lactic acid bacteria made the gene Il10 upregulated, Il10 had a significant effect on tumor volume reduction and prolongation of mouse survival, and played a role through cytokine receptor interaction pathway.
Published in
Oleanolic acid inhibits the tumor progression by regulating Lactobacillus through the cytokine-cytokine receptor interaction pathway in 4T1-induced mice breast cancer model
He K, Meng X, Su J et al. · Heliyon 2024 · PMID 38449659 · doi:10.1016/j.heliyon.2024.e27028
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Also filed as BioProject PRJNA966979 and SRA study SRP435782. Searching any of these in the dataset finder brings you back here.

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