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Spatially resolved transcriptome of brain white matter brain lesions of a patient with progressive multiple sclerosis

GSE231586 Homo sapiens Expression profiling by high throughput sequencing 8 samples Submitted 2024/06/21 Platform GPL24676
Summary
Different lesion types were microdissected out from snap-frozen white matter and placed on visium slides. Optimization of RNA release and visualization with Nikon Ecclipse Ti2 were followed by barcoded recover, library preparation and sequencing.
Published in
Single-Cell Multi-Omics Map of Cell Type-Specific Mechanistic Drivers of Multiple Sclerosis Lesions
Elkjaer ML, Hartebrodt A, Oubounyt M et al. · Neurology(R) neuroimmunology & neuroinflammation 2024 · PMID 38564686 · doi:10.1212/NXI.0000000000200213
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Also filed as BioProject PRJNA967121 and SRA study SRP436075. Searching any of these in the dataset finder brings you back here.

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