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Respiratory Syncytial virus (RSV)

GSE232687 Homo sapiens (human) Non-coding RNA profiling 44 samples Submitted 2024/05/29 Platform GPL30173Platform GPL24676
At a glance

Non-coding RNA profiling · human · 44 samples

What it is
Non-coding RNA profilingLevels of RNAs that do not code for proteins, such as miRNA or lncRNA.
Organism
Homo sapiens (human)
Samples
44 samples: 11 conditions, mostly in triplicateGroups are read from the sample names, not from the paper. Check the list below.
Data you can get
A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Paper
RNA-RNA interactions between respiratory syncytial virus and miR-26 and miR-27 are associated with regulation of cell cycle and antiviral immunityNucleic acids research · 2024
SuperSeries — this record groups several sub-series.
Summary (written by the submitters)
This SuperSeries is composed of the SubSeries listed below.
Published in
RNA-RNA interactions between respiratory syncytial virus and miR-26 and miR-27 are associated with regulation of cell cycle and antiviral immunity
Ressel S, Kumar S, Bermúdez-Barrientos JR et al. · Nucleic acids research 2024 · PMID 38412296 · doi:10.1093/nar/gkae116
This dataset
Open GSE232687 in finder → Find more human datasets →
Download · which file do I need?

Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.

1 · Just have a look

Processed table

The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.

Series matrix ↓
2 · Re-analyse it

Supplementary files

The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE232687_RAW.tar (it can run to tens of gigabytes).

All supplementary files ↗ Whole study · RAW.tar ↓
3 · Start from the raw reads

Raw sequencing reads

The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.

Raw reads on ENA ↗

Also filed as BioProject PRJNA973580 and SRA study SRP436118. Searching any of these in the dataset finder brings you back here.

NCBI GEO page ↗ Paper (PMID 38412296) ↗
Study design
11 conditions, mostly in triplicate
A549 Mock-infected, 48 hpi, polyphosphatase-t… ×3 A549 RSV-infected, 48 hpi, polyphosphatase-tr… ×3 A549 miR-27a shMIMIC clone 1, Mock-infected, ×3 A549 WT, Mock-infected ×3 A549 miR-27a & miR-27b mimic transfected, Moc… ×3 A549 miR-27a & miR-27b inhibitor transfected,… ×3 A549 Mock-infected, total RNA ×3 A549 RSV-infected, total RNA ×3 +17 more

Supports a case/control comparison: 6 samples read as cases, 3 as controls.

How we read this: 11 replicated groups read from 44 sample titles; they account for 30 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.

Samples in this study

+ 4 more — browse all 44 samples with per-sample file links →

Datasets on a similar topic

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Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.