Gene expression profile at single cell level of cultured normal human epidermal melanocytes (NHEMs) [NHEM_FSK_scRNA]
Single-cell RNA-seq · human · 2 samples
- What it is
- Single-cell RNA-seqGene activity measured in thousands of individual cells, so cell types can be told apart.
- Organism
- Homo sapiens (human)
- Samples
- 2 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Distinct melanocyte subpopulations defined by stochastic expression of proliferation or maturation programs enable a rapid and sustainable pigmentation responsePLoS biology · 2024
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE233137_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Single-cell studies usually ship their counts as 10x files (matrix.mtx, barcodes.tsv, features.tsv), an .h5 file, or an .rds / .h5ad object that Seurat or Scanpy can open. Look for those among the supplementary files.
Also filed as BioProject PRJNA975105 and SRA study SRP438948. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 2 more — browse all 2 samples with per-sample file links →
- GSE284779 RNA-sequencing of melanoma celllines compared to normal human melanocytes (NHEMs) 14 samples shares nhem, melanocytes, normal, nhems
- GSE230574 Gene expression profile at single cell level of human melanoma cell lines, normal human melanocytes and human nevus cells. 2 samples shares melanocytes, normal, level
- GSE245608 Transcriptomic evaluation of skin tape-strips in children with allergic asthma uncovers epidermal barrier dysfunction and asthma-associated biomarkers abnormalities 32 samples shares epidermal, normal
- GSE338364 Lentiviral hTERT overexpression extends the lifespan of primary human epidermal melanocytes and reshapes transcriptional programs 24 samples shares melanocytes, epidermal
- GSE272551 Phosphodiesterase-4 inhibitors increase pigment cells proliferation and melanization in cultured melanocytes and within a 3D skin equivalent model 24 samples shares melanocytes, cultured
- GSE252347 RNA-Seq of human cutaneous squamous cell carcinoma cell lines and normal human epidermal keratinocytes. 12 samples shares epidermal, normal
- GSE245859 Treatment with cultured epidermal autograft from revertant skin for epidermolytic ichthyosis 4 samples shares epidermal, cultured
- GSE66359 Analysis of the gene expression profile in normal human epidermal keratinocytes and cutaneous squamous cell carcinoma cell lines 13 samples shares epidermal, normal
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.