← BioTransfer GEO Dataset Finder
GEO series

Unexpected nuclear hormone receptor and chromatin dynamics regulate estrous cycle dependent gene expression

GSE234065 Mus musculus (mouse) ChIP-seq / ATAC-seq (genome binding and open chromatin) 32 samples Submitted 2024/08/01 Platform GPL21103Platform GPL24247Platform GPL13112
At a glance

ChIP-seq / ATAC-seq (genome binding and open chromatin) · mouse · 32 samples

What it is
ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
Organism
Mus musculus (mouse)
Samples
32 samples: 6 conditions, mostly with about 4 replicates eachGroups are read from the sample names, not from the paper. Check the list below.
Data you can get
A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Paper
Unexpected nuclear hormone receptor and chromatin dynamics regulate estrous cycle dependent gene expressionNucleic acids research · 2024
SuperSeries — this record groups several sub-series.
Summary (written by the submitters)
This SuperSeries is composed of the SubSeries listed below.
Published in
Unexpected nuclear hormone receptor and chromatin dynamics regulate estrous cycle dependent gene expression
Jefferson WN, Wang T, Padilla-Banks E et al. · Nucleic acids research 2024 · PMID 39166489 · doi:10.1093/nar/gkae714
This dataset
Download · which file do I need?

Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.

1 · Just have a look

Processed table

The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.

2 · Re-analyse it

Supplementary files

The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE234065_RAW.tar (it can run to tens of gigabytes).

3 · Start from the raw reads

Raw sequencing reads

The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.

What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.

Also filed as BioProject PRJNA979252 and SRA study SRP440892. Searching any of these in the dataset finder brings you back here.

Study design
6 conditions, mostly with about 4 replicates each
Adult CoD RNA-seq ×4 Adult WT CoD RNA-seq ×4 Adult HIF2A cKO CoD RNA-seq ×4 Adult CoE RNA-seq ×3 Adult WT CoE RNA-seq ×3 Adult HIF2A cKO CoE RNA-seq ×3 Adult CoD ATAC-seq ×1 Adult CoE ATAC-seq ×1 +9 more

Supports a between-group comparison across 21 samples.

How we read this: 6 replicated groups read from 32 sample titles; they account for 21 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.

Samples in this study
Datasets on a similar topic

Search all mouse ChIP / ATAC / CUT&Tag datasets in GEO →

Share this dataset

Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.