m6Am sequesters PCF11 to promote full-length transcription
ChIP-seq / ATAC-seq (genome binding and open chromatin) · human · 99 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Homo sapiens (human)
- Samples
- 99 samples: 20 conditions, mostly in triplicateGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- m(6)Am sequesters PCF11 to suppress premature termination and drive neuroblastoma differentiationMolecular cell · 2024
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE234137_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA980168 and SRA study SRP440639. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 60 samples.
How we read this: 20 replicated groups read from 99 sample titles; they account for 60 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM7438397 WT HEK293T, PCF11
- GSM7438398 WT HEK293T, Input
- GSM7438399 Pcif1-KO HEK293T, PCF11
- GSM7438400 Pcif1-KO HEK293T, Input
- GSM7446541 WT HEK293T siScram PCT 1 WT HEK293T siScram PCT
- GSM7446542 WT HEK293T siScram PCT 2 WT HEK293T siScram PCT
- GSM7446543 WT HEK293T siScram PCT 3 WT HEK293T siScram PCT
- GSM7446544 WT HEK293T siPCF11 PCT 1 WT HEK293T siPCF11 PCT
- GSM7446545 WT HEK293T siPCF11 PCT 2 WT HEK293T siPCF11 PCT
- GSM7446546 WT HEK293T siPCF11 PCT 3 WT HEK293T siPCF11 PCT
- GSM7446547 Pcif1-KO HEK293T siScram PCT 1 Pcif1-KO HEK293T siScra…
- GSM7446548 Pcif1-KO HEK293T siScram PCT 2 Pcif1-KO HEK293T siScra…
- GSM7446549 Pcif1-KO HEK293T siScram PCT 3 Pcif1-KO HEK293T siScra…
- GSM7446550 Pcif1-KO HEK293T siPCF11 PCT 1 Pcif1-KO HEK293T siPCF1…
- GSM7446551 Pcif1-KO HEK293T siPCF11 PCT 2 Pcif1-KO HEK293T siPCF1…
- GSM7446552 Pcif1-KO HEK293T siPCF11 PCT 3 Pcif1-KO HEK293T siPCF1…
- GSM7446553 WT HEK293T no siDis3 control 1 WT HEK293T no siDis3 co…
- GSM7446554 WT HEK293T no siDis3 control 2 WT HEK293T no siDis3 co…
- GSM7446555 WT HEK293T no siDis3 control 3 WT HEK293T no siDis3 co…
- GSM7446556 Pcif1-KO HEK293T no siDis3 control 1 Pcif1-KO HEK293T no siD…
- GSM7446557 Pcif1-KO HEK293T no siDis3 control 2 Pcif1-KO HEK293T no siD…
- GSM7446558 Pcif1-KO HEK293T no siDis3 control 3 Pcif1-KO HEK293T no siD…
- GSM7446568 WT_siScram_anabolicSLAM
- GSM7446569 WT_siPCF11_anabolicSLAM
- GSM7446570 Pcif1-KO_siScram_anabolicSLAM
- GSM7446571 Pcif1-KO_siPCF11_anabolicSLAM
- GSM7446575 WT_catabolicSLAM_0hPost-s4U
- GSM7446576 WT_catabolicSLAM_3hPost-s4U
- GSM7446577 WT_catabolicSLAM_6hPost-s4U
- GSM7446578 WT_catabolicSLAM_12hPost-s4U
- GSM7446579 Pcif1-KO_catabolicSLAM_0hPost-s4U
- GSM7446580 Pcif1-KO_catabolicSLAM_3hPost-s4U
- GSM7446581 Pcif1-KO_catabolicSLAM_6hPost-s4U
- GSM7446582 Pcif1-KO_catabolicSLAM_12hPost-s4U
- GSM7921179 WT HEK293T, S2P
- GSM7921180 Pcif1-KO HEK293T, S2P
- GSM7921181 WT+siScram HEK293T, Input
- GSM7921182 Pcif1-KO+siScram HEK293T, Input
- GSM7921183 WT+siPcf11 HEK293T, Input
- GSM7921184 Pcif1-KO+siPcf11 HEK293T, Input
+ 59 more — browse all 99 samples with per-sample file links →
- GSE233877 m6Am sequesters PCF11 to promote full-length transcription [ChIP-Seq] 14 samples shares pcf11, m6am, transcription, full-length, sequesters, promote
- GSE300575 Cohesin acts as a transcriptional gatekeeper by restraining pause–release to promote processive elongation [ChIP-seq] 22 samples shares transcription, promote
- GSE299348 Single-cell epigenetic, transcriptional, protein, and TCR states of HIV-1-infected cells in gut 117 samples shares transcription
- GSE314310 Cardiopedia-Ligand: a Ligand Stimulation Atlas for Cardiac Function and Transcriptional Response 468 samples shares transcription
- GSE303576 Rb-driven transcription limits its tumour suppressive effects in breast cancer 279 samples shares transcription
- GSE22098 Whole blood transcriptional profiles of patients with active tuberculosis (TB) and other inflammatory and infectious diseases 274 samples shares transcription
- GSE303478 Systematic investigation reveals extensive Epstein-Barr virus transcriptional regulation of the human genome 217 samples shares transcription
- GSE271676 Spatial Transcriptional Landscape of Human Heart Failure 178 samples shares transcription
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.