GEO series
RFX6 haploinsufficiency predisposes to diabetes through impaired beta cell function
GSE234289
Homo sapiens
Expression profiling by high throughput sequencing
24 samples
2024/04/11
GPL24676
Summary
We performed bulk RNA-seq analysis for CRISPR-Cpf1 mutated H1 cells that were differentiated into pancreatic cells. Homozygous mutant was compared to control cells (RFX6-/- vs RFX6+/+) at stage 3 (PF) and stage 5 (EP), and heterozygous mutant was compared to control cells (RFX6-/+ vs RFX6+/+) at stage 7 (SC-islets).
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Paper (PMID 38743124) ↗
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