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Comparative 3D genome analysis between neural retina and RPE reveals differential cis-regulatory interactions at retinal disease loci

GSE236022 Homo sapiens (human) ChIP-seq / ATAC-seq (genome binding and open chromatin) 53 samples Submitted 2024/04/08 Platform GPL24676Platform GPL23227
At a glance

ChIP-seq / ATAC-seq (genome binding and open chromatin) · human · 53 samples

What it is
ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
Organism
Homo sapiens (human)
Samples
53 samples: 42 distinct titles, 7 of them repeatedGroups are read from the sample names, not from the paper. Check the list below.
Data you can get
A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Paper
Comparative 3D genome analysis between neural retina and retinal pigment epithelium reveals differential cis-regulatory interactions at retinal disease lociGenome biology · 2024
SuperSeries — this record groups several sub-series.
Summary (written by the submitters)
This SuperSeries is composed of the SubSeries listed below.
Published in
Comparative 3D genome analysis between neural retina and retinal pigment epithelium reveals differential cis-regulatory interactions at retinal disease loci
D'haene E, López-Soriano V, Martínez-García PM et al. · Genome biology 2024 · PMID 38760655 · doi:10.1186/s13059-024-03250-6
This dataset
Open GSE236022 in finder → Find more human datasets →
Download · which file do I need?

Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.

1 · Just have a look

Processed table

The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.

Series matrix ↓
2 · Re-analyse it

Supplementary files

The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE236022_RAW.tar (it can run to tens of gigabytes).

All supplementary files ↗ Whole study · RAW.tar ↓
3 · Start from the raw reads

Raw sequencing reads

The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.

Raw reads on ENA ↗

What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.

Also filed as BioProject PRJNA988443 and SRA study SRP445771. Searching any of these in the dataset finder brings you back here.

NCBI GEO page ↗ Paper (PMID 38760655) ↗
Study design
42 distinct titles, 7 of them repeated
HiC RPE/choroid, ×4 HiC neural retina, ×4 UMI-4C in human neural retina, ABCA4 Interact… ×2 UMI-4C in human neural retina, ABCA4 Interact… ×2 UMI-4C in human neural retina, ABCA4 Interact… ×2 HiChIP H3K4me3 RPE/choroid, ×2 HiChIP H3K4me3 neural retina, ×2

How we read this: Read from 53 sample titles: 42 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.

Samples in this study

+ 13 more — browse all 53 samples with per-sample file links →

Datasets on a similar topic

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Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.