E-cadherin regulates female tumor aggressiveness by controlling estrogen-sensitivity [ChIP-seq]
ChIP-seq / ATAC-seq (genome binding and open chromatin) · mouse · 13 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Mus musculus (mouse)
- Samples
- 13 samples: 13 samples, each with a distinct title — no replicated groupsGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Targeting GRPR for sex hormone-dependent cancer after loss of E-cadherinNature · 2025
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE237500_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA995537 and SRA study SRP449876. Searching any of these in the dataset finder brings you back here.
Any grouping that defines a comparison lives in the sample characteristics, which GEO records separately from the titles.
How we read this: Read from 13 sample titles: 13 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM7622286 Ma_1007,Male,Ecad,H3K27ac
- GSM7622287 Ma_1181,Male,Ecad,H3K27ac
- GSM7622288 Ma_1014,Female,Ecad,H3K27ac
- GSM7622289 Ma_1039,Female,Ecad,H3K27ac
- GSM7622290 Ma_1062,Male,ΔEcad,H3K27ac
- GSM7622291 Ma_1456,Male,ΔEcad,H3K27ac
- GSM7622292 Ma_1057,Female,ΔEcad,H3K27ac
- GSM7622293 Ma_1064,Female,ΔEcad,H3K27ac
- GSM7622294 Ma_1069,Female,ΔEcad,H3K27ac
- GSM7622295 Male,Ecad,Input
- GSM7622296 Female,Ecad,Input
- GSM7622297 Male,ΔEcad,Input
- GSM7622298 Female,ΔEcad,Input
- GSE242901 An Intrinsically Disordered Region Controlling Condensation of a Circadian Clock Component and Rhythmic Transcription in the Liver [ChIP-seq] 45 samples shares controlling, chip-seq
- GSE276621 Reciprocal genetic screens identify epigenetics factors controlling epidermal cell activation. [ChIP-Seq] 36 samples shares controlling, chip-seq
- GSE280195 Leukemia aggressiveness is driven by chromatin remodeling and expression changes of core regulators [ChIP-seq] 25 samples shares aggressiveness, chip-seq
- GSE276308 Two mutations associated with leukemia that change a single tyrosine residue in the STAT5B SH2 domain have opposite effects on the transcriptional programs controlling hematopoiesis [ChIP-seq] 13 samples shares controlling, chip-seq
- GSE278413 Malat1 regulates female Th2 cell cytokine expression through controlling early differentiation and response to IL-2 16 samples shares controlling, female
- GSE241351 Iron reshapes polyamine metabolism through controlling exosomal miR-33a secretion to remodel extracellular matrix in tumor microenvironment 6 samples shares controlling
- GSE269192 ZEB2 is a Master Switch Controlling the Tumor-Associated Macrophage Program 493 samples shares controlling
- GSE269188 ZEB2 is a Master Switch Controlling the Tumor-Associated Macrophage Program [KO_screen] 331 samples shares controlling
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.