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RNA sequencing (RNA-seq) of ANKRD6 in MKN45 gastric cancer cells by shRNA

GSE238103 Homo sapiens Expression profiling by high throughput sequencing 8 samples Submitted 2024/04/10 Platform GPL28038
Summary
Metastasis and recurrence are the major causes of poor outcome in gastric cancer (GC). We showed that ANKRD6 expression is associated with a poorer prognosis in 10 independent GC cohorts and with metastatic states and processes. Here, by transcriptomic profiling we have characterized the effect of ANKRD6 silencing in vitro and found that cells with ANKRD6 downregulation display an impairment in key metastatic processes such as the Epithelial-mesenchymal transition.
Published in
Identification and validation of a novel angiogenesis-related gene signature for predicting prognosis in gastric adenocarcinoma
Xu P, Liu S, Song S et al. · Frontiers in oncology 2022 · PMID 36727080 · doi:10.3389/fonc.2022.965102
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Also filed as BioProject PRJNA997969 and SRA study SRP451742. Searching any of these in the dataset finder brings you back here.

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