GEO series
Effects of the C5aR1 blockade, Poly I:C and anti/PD1 combined treatment in the gene expression in LLC tumors
GSE239485
Mus musculus
Expression profiling by high throughput sequencing
24 samples
2024/11/20
GPL30172
Summary
In syngeneic solid tumor models, C5aR1 inhibition significantly enhanced the effectiveness of poly I:C, a toll-like receptor 3 (TLR3) agonist, combined with Programmed cell death protein 1 (PD-1)/Programmed cell death ligand-1 (PD-L1) blockade. In this experiment we aim to determine the effects of C5aR1 inhibition in the genes expression of Lewis Lung Cancer (LLC) tumors treated with poly I:C and PD-1 blockade combined treatment.
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