DNA methylation status determines the sensitivity of repeats to restriction by the HUSH-MORC2 complex [Bulk RNA-seq]
DNA methylation · human · 27 samples
- What it is
- DNA methylationChemical marks on DNA that help switch genes on or off.
- Organism
- Homo sapiens (human)
- Samples
- 27 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- DNA methylation governs the sensitivity of repeats to restriction by the HUSH-MORC2 corepressorNature communications · 2024
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE240386_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for beta-value tables or raw IDAT files among the supplementary files.
Also filed as BioProject PRJNA1003480 and SRA study SRP454063. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 27 more — browse all 27 samples with per-sample file links →
- GSE242143 DNA methylation status determines the sensitivity of repeats to restriction by the HUSH-MORC2 complex 75 samples shares hush-morc2, methylation, sensitivity, restriction, determines, repeats, complex
- GSE253785 Bone morphogenetic protein (BMP) signaling determines neuroblastoma cell fate and sensitivity to retinoic acid [RNA-seq] 17 samples shares sensitivity, determines, rna-seq
- GSE271704 5G-exposed human skin cells do not respond with altered gene expression and methylation profiles [RNA-Seq] 120 samples shares methylation, rna-seq
- GSE274999 Clinical response to azacitidine in MDS is associated with distinct DNA methylation changes in HSPCs [RNA-Seq] 52 samples shares methylation, rna-seq
- GSE284289 Removal of promoter DNA methylation by epigenome editing reverses HBG silencing [RNA-seq] 40 samples shares methylation, rna-seq
- GSE292130 Longitudinal changes in DNA methylation in IDH-mutant glioma fuel disease progression through altered cell state differentiation [scRNA-seq] 31 samples shares methylation, rna-seq
- GSE274217 METTL3-dependent m6A RNA methylation represses transposable elements derived enhancers to suppress naïve pluripotency in human pluripotent stem cells [RNA-Seq] 28 samples shares methylation, rna-seq
- GSE302178 Umbilical Cord Blood Cell Transcriptional and Methylation Signatures at Birth Are Associated with BPD Development [RNA-Seq] 27 samples shares methylation, rna-seq
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.