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Gene expression profile at single cell level of immune cells following spinal cord injury

GSE240727 Mus musculus Expression profiling by high throughput sequencing 6 samples Submitted 2025/09/16 Platform GPL24247
Summary
Immune cells infiltrate extensively into the lesion area after spinal cord injury and persist chronically, playing a crucial role in the inflammation and recovery of spinal cord injury. Here we investigated gene expression levels at single cell level of immune cells which distribute in the uninjured spinal cord and the lesion area at 1, 3, 7, 14, and 28 days after spinal cord injury. Heterogeneity analysis was performed to reveal the immune response after injury and how it is altered over time.
Published in
Neutrophil extracellular traps released by CD177(+) neutrophils aggravated inflammation and neuronal impairment post-SCI
Dai S, Zheng Z, Zhang C et al. · Cell communication and signaling : CCS 2025 · PMID 41353336 · doi:10.1186/s12964-025-02553-w
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Also filed as BioProject PRJNA1005168 and SRA study SRP454892. Searching any of these in the dataset finder brings you back here.

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