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Kinetic chromatin openin profiles in mouse ApcDHep or wt hepatocytes

GSE242267 Mus musculus Genome binding/occupancy profiling by high throughput sequencing 4 samples Submitted 2024/04/24 Platform GPL17021
Summary
We analyzed chromatin opening in hepatocytes isolated from Apclox/loxlivers, after injection of adenovirus Ad5 -Cre-GFP and sorting on the basis of GFP signal at day 6, 15 and 21 post-injection. Our aims was to study the impact of an aberrant beta-catenin activation on chromatin opening in hepatocytes during the early steps of liver tumorigenesis.
Published in
Wnt, glucocorticoid and cellular prion protein cooperate to drive a mesenchymal phenotype with poor prognosis in colon cancer
Mouillet-Richard S, Gougelet A, Passet B et al. · Journal of translational medicine 2024 · PMID 38589873 · doi:10.1186/s12967-024-05164-0
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Also filed as BioProject PRJNA1012732 and SRA study SRP458357. Searching any of these in the dataset finder brings you back here.

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