Collagen signaling and matrix stiffness regulate multipotency in glandular epithelial stem cells in mice
Expression microarray · mouse · 12 samples
- What it is
- Expression microarrayGene activity read on a chip (the older technology that RNA-seq replaced).
- Organism
- Mus musculus (mouse)
- Samples
- 12 samples: 2 × Basal cell P13, Tip vs 2 × Basal cell P13, Duct vs 2 × BC transplant vs 2 × ControlGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed expression table (series matrix) and the array files, from NCBI.
- Paper
- Collagen signaling and matrix stiffness regulate multipotency in glandular epithelial stem cells in miceNature communications · 2024
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE243338_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For arrays the series matrix is normally the normalised expression table you want; the raw array files (CEL and similar) are in the RAW.tar.
Also filed as BioProject PRJNA1017844 and SRA study SRP462026. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 8 samples.
How we read this: 4 replicated groups read from 12 sample titles; they account for 8 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM7783601 COL1 and STIFF, GEX
- GSM7783602 COL1 and STIFF, HTO
- GSM7783603 MATR and SOFT, GEX
- GSM7783604 MATR and SOFT, HTO
- GSM7783605 Basal cell P13, Tip 1 Basal cell P13, Tip
- GSM7783606 Basal cell P13, Tip 2 Basal cell P13, Tip
- GSM7783607 Basal cell P13, Duct 1 Basal cell P13, Duct
- GSM7783608 Basal cell P13, Duct 2 Basal cell P13, Duct
- GSM7783609 BC transplant 1 BC transplant
- GSM7783610 BC transplant 2 BC transplant
- GSM7783611 Control 1 Control
- GSM7783612 Control 2 Control
- GSE276126 STAT1 regulates immune-mediated intestinal stem cell proliferation and epithelial regeneration 13 samples shares epithelial, regulate, stem
- GSE205411 Multiple subpopulations in medullary thymic epithelial cells are regulated by Aire with distinctive modes of gene regulations 2219 samples shares epithelial, regulate
- GSE311705 Uterine epithelial ERα regulates preimplantation uterine luminal epithelial (LE) and uterine mRNAs 59 samples shares epithelial, regulate
- GSE205410 Multiple subpopulations in medullary thymic epithelial cells are regulated by Aire with distinctive modes of gene regulations [bulkRNA-seq] 47 samples shares epithelial, regulate
- GSE220665 The Transcriptional Cofactor SKI Regulates Medullary Thymic Epithelial Cell Differentiation and Peripheral T Cell Responses 42 samples shares epithelial, regulate
- GSE248933 Transcriptomic and epigenomic profiling of Tet TKO neural stem cells to study NSC specification and multipotency 36 samples shares multipotency, stem
- GSE245259 The soluble factor milieu in IPF and in COPD exacerbations dysregulates epithelial differentiation 30 samples shares epithelial, regulate
- GSE272476 Neutrophils exposed to a cholesterol metabolite secrete extracellular vesicles that promote epithelial-mesenchymal transition and stemness in breast cancer cells [RNA-seq] 30 samples shares epithelial, stem
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.