X chromosome encoded histone demethylase UTX regulates mammalian axon regeneration via microRNA-124
RNA-seq (gene expression) · mouse · 13 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 13 samples: 5 conditions, mostly in triplicateGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Roles of Kdm6a and Kdm6b in Regulation of Mammalian Neural RegenerationAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE244243_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1021989 and SRA study SRP463677. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 13 samples.
How we read this: 5 replicated groups read from 13 sample titles; they account for 13 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM7809907 RGCs of UTX-AAV2-Cre mice (P42) 1 RGCs of UTX-AAV2-Cre mi…
- GSM7809908 RGCs of UTX-AAV2-Cre mice (P42) 2 RGCs of UTX-AAV2-Cre mi…
- GSM7809909 RGCs of UTX-AAV2-GFP mice (P42) 1 RGCs of UTX-AAV2-GFP m…
- GSM7809910 RGCs of UTX-AAV2-GFP mice (P42) 2 RGCs of UTX-AAV2-GFP m…
- GSM7809911 RGCs of UTX-AAV2-GFP mice (P42) 3 RGCs of UTX-AAV2-GFP m…
- GSM7809912 RGCs of WT mice (P1) 1 RGCs of WT mice (P1)
- GSM7809913 RGCs of WT mice (P1) 2 RGCs of WT mice (P1)
- GSM7809914 RGCs of WT mice (P1) 3 RGCs of WT mice (P1)
- GSM7809915 RGCs of WT mice (P14) 1 RGCs of WT mice (P14)
- GSM7809916 RGCs of WT mice (P14) 2 RGCs of WT mice (P14)
- GSM7809917 RGCs of WT mice (P14) 3 RGCs of WT mice (P14)
- GSM7809918 RGCs of WT mice (P21) 1 RGCs of WT mice (P21)
- GSM7809919 RGCs of WT mice (P21) 2 RGCs of WT mice (P21)
- GSE239950 Effect of KDM5 histone demethylase in 3T3-L1 differentiation 29 samples shares demethylase, histone
- GSE286059 Intrinsically disordered regions restrain genomic targeting of RNA and histone demethylases in mammals and plants [EU] 24 samples shares demethylase, histone
- GSE202300 KDM6 Histone Demethylases Tune Pancreatic Cancer Plasticity 17 samples shares demethylase, histone
- GSE276119 Hyperinnervation inhibits organ-level regeneration in mammalian skin 16 samples shares regeneration, mammalian
- GSE276730 The histone lysine demethylase KDM7A contributes to reward memory via Fscn1-induced synaptic plasticity in the medial prefrontal cortex 16 samples shares demethylase, histone
- GSE286064 Intrinsically disordered regions restrain genomic targeting of RNA and histone demethylases in mammals and plants [Histone_LCD_RNA] 16 samples shares demethylase, histone
- GSE311802 Autism-like phenotypes and increased NMDAR2D expression in mice with KDM5B histone lysine demethylase deficiency 16 samples shares demethylase, histone
- GSE274858 Hyaluronic acid networks and emergent tissue mechanics orchestrate mammalian limb regeneration 11 samples shares regeneration, mammalian
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.