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Spatial transcriptomics reveals key differences in Alport disease progression and potential targets of hEV treatment in Alport disease

GSE245039 Mus musculus Expression profiling by high throughput sequencing 6 samples Submitted 2024/11/30 Platform GPL24247
Summary
Alport syndrome is a glomerular disease. To understand the disease progression of alport syndrome and potential therapeutical effects of hEV derived from AFSCs, we performed spatial transcriptomics to profile the heterogeniety of cell populations in kidneys of mouse of AS through disease progression and hEV treated AS mice as well. Our analysis sheds light on key functional parts of the kidney responsible in disease progression as well as potential targets of hEV therapy.
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Direct links to NCBI, no account and no request form: the whole study as GSE245039_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 6 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1027091 and SRA study SRP465952. Searching any of these in the dataset finder brings you back here.

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