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Quantitative Analysis of erythroblast cells Transcriptomes treated with Carbon Dots(CDs) derived from Codonopsis pilosula or not

GSE245893 Mus musculus Expression profiling by high throughput sequencing 6 samples Submitted 2024/12/31 Platform GPL23479
Summary
In this study, distinctive biological CDs derived from Codonopsis pilosula were designed and synthesized. In traditional Chinese medicine, Codonopsis pilosula is considered to be a good blood tonic. The synthesized CDs comprise sp2/sp3 carbon atoms and oxygen/nitrogen-based groups and exhibit good biocompatibility and membrane permeability. The in vitro and in vivo experiments were conducted using an erythroid differentiation system and a mouse model, respectively, and showed that the CDs significantly promote the proliferation of erythroid cells. To reveal the detailed mechanisms of CDs in stimulating erythroblast proliferation, we performed RNA sequencing to analyze the gene expression profile change between untreated andmCDs treated erythroblasts.
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Also filed as BioProject PRJNA1030350 and SRA study SRP467551. Searching any of these in the dataset finder brings you back here.

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