A brain-enriched circular RNA controls excitatory neurotransmission and restricts sensitivity to aversive stimuli
RNA-seq (gene expression) · mouse · 22 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 22 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- A brain-enriched circular RNA controls excitatory neurotransmission and restricts sensitivity to aversive stimuliScience advances · 2024
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE246304_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1032476 and SRA study SRP468557. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 22 more — browse all 22 samples with per-sample file links →
- GSE290856 Excitatory Neuron-Derived Interleukin-34 Controls Cortical Developmental Microglia Function 30 samples shares excitatory, controls
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- GSE314901 Ketogenic diet dampens excitatory neurotransmission by shrinking synaptic vesicle pools 20 samples shares neurotransmission, excitatory
- GSE264436 RIPK3 promotes neuronal survival by suppressing excitatory neurotransmission during CNS viral infection 18 samples shares neurotransmission, excitatory
- GSE310481 Ketogenic diet dampens excitatory neurotransmission by shrinking synaptic vesicle pools 16 samples shares neurotransmission, excitatory
- GSE300997 Persistent cortical excitatory neuron dysregulation in adult Chd8 haploinsufficient mice 127 samples shares excitatory
- GSE287818 Molecular and cellular rhythms in excitatory and inhibitory neurons in the mouse prefrontal cortex 114 samples shares excitatory
- GSE283699 Unique gene expression in Down syndrome mouse model contingent on spatial subregion in excitatory hippocampal neurons during early midlife 81 samples shares excitatory
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.