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Multiome single-cell RNA and ATAC sequencing from Young and Old Hematopoietic Stem Cells (HSCs)

GSE246464 Mus musculus Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing 8 samples Submitted 2025/06/02 Platform GPL24247
Summary
We used multiome single cell RNA and ATAC (scRNA+scATAC) sequencing to analyze the heterogeneity in young and old HSCs
Published in
Kit(lo) hematopoietic stem cells exhibit distinct lymphoid-primed chromatin landscapes that enhance thymic reconstitution
Elias HK, Mitra S, da Silva MB et al. · Nature communications 2025 · PMID 40615375 · doi:10.1038/s41467-025-61125-1
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Also filed as BioProject PRJNA1032972 and SRA study SRP468923. Searching any of these in the dataset finder brings you back here.

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