GEO series
Epigenetic reprogramming of intestinal stemness by dietary arachidonic acid [CutnRun 1]
GSE246875
Mus musculus
Genome binding/occupancy profiling by high throughput sequencing
12 samples
2025/11/01
GPL19057
Summary
We evaluated tthe necessity of PGE2-Ptger4 signaling in regulating stemness enhancing effects of arachidonic acid (AA) via CutnRun and found that Ptger4 KO organoids failed to cause global methylation changes in signature genes that are associated with stem cell reprogramming in response to AA or PGE2.
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