The chromatin loop release factor WAPL regulates EBV latency status by restricting LMP production [RNA-seq]
RNA-seq (gene expression) · human · 12 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 12 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- The DNA loop release factor WAPL suppresses Epstein-Barr virus latent membrane protein expression to maintain the highly restricted latency I programPLoS pathogens · 2024
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE248336_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1043233 and SRA study SRP473130. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 12 more — browse all 12 samples with per-sample file links →
- GSE95015 The cohesin release factor WAPL restricts chromatin loop extension. 63 samples shares wapl, chromatin, release
- GSE95014 The cohesin release factor WAPL restricts chromatin loop extension. [HiC-Seq] 14 samples shares wapl, chromatin, release
- GSE95520 The cohesin release factor WAPL restricts chromatin loop extension [DamID] 12 samples shares wapl, chromatin, release
- GSE324842 Transcriptomic analysis of Primary B-cell target genes upon infection with Epstein-Barr Virus (EBV) expressing wildtype (WT) or mutant Latent Membrane Protein 1 (LMP1) 25 samples shares ebv, lmp
- GSE244312 Unstable EBV latency drives inflammation in multiple sclerosis patient derived spontaneous B cells [Batch1] 24 samples shares ebv, latency
- GSE244314 Unstable EBV latency drives inflammation in multiple sclerosis patient derived spontaneous B cells [Batch3] 18 samples shares ebv, latency
- GSE244313 Unstable EBV latency drives inflammation in multiple sclerosis patient derived spontaneous B cells [Batch2] 14 samples shares ebv, latency
- GSE102884 Topologically associating domains and chromatin loops depend on cohesin and are regulated by CTCF, WAPL and PDS5 proteins 30 samples shares wapl, chromatin
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.