← BioTransfer GEO Dataset Finder
GEO series

Whole transcriptome gene expression in Alzheimer's disease (AD) patients

GSE248423 Homo sapiens (human) Non-coding RNA profiling 196 samples Submitted 2026/03/11 Platform GPL24676
At a glance

Non-coding RNA profiling · human · 196 samples

What it is
Non-coding RNA profilingLevels of RNAs that do not code for proteins, such as miRNA or lncRNA.
Organism
Homo sapiens (human)
Samples
196 samples: 49 × Blood_AD vs 49 × Blood_Control vs 49 × Blood_AD_Short Read vs 49 × Blood_Control_Short ReadGroups are read from the sample names, not from the paper. Check the list below.
Data you can get
A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Paper
An RNA biomarker panel for the diagnosis of Alzheimer's disease from whole bloodAlzheimer's research & therapy · 2026
SuperSeries — this record groups several sub-series.
Summary (written by the submitters)
This SuperSeries is composed of the SubSeries listed below.
Published in
An RNA biomarker panel for the diagnosis of Alzheimer's disease from whole blood
Paz S, Robishaw JD, Caputi M · Alzheimer's research & therapy 2026 · PMID 41620770 · doi:10.1186/s13195-026-01977-x
This dataset
Open GSE248423 in finder → Find more human datasets →
Download · which file do I need?

Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.

1 · Just have a look

Processed table

The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.

Series matrix ↓
2 · Re-analyse it

Supplementary files

The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE248423_RAW.tar (it can run to tens of gigabytes).

All supplementary files ↗ Whole study · RAW.tar ↓
3 · Start from the raw reads

Raw sequencing reads

The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.

Raw reads on ENA ↗

Also filed as BioProject PRJNA1043722 and SRA study SRP473380. Searching any of these in the dataset finder brings you back here.

NCBI GEO page ↗ Paper (PMID 41620770) ↗
Study design
49 × Blood_AD vs 49 × Blood_Control vs 49 × Blood_AD_Short Read vs 49 × Blood_Control_Short Read

Supports a between-group comparison across 196 samples.

How we read this: 4 replicated groups read from 196 sample titles; they account for 196 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.

Samples in this study

+ 156 more — browse all 196 samples with per-sample file links →

Datasets on a similar topic

Search all human datasets in GEO →

Share this dataset

Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.