EIF3D Safeguards the Homeostasis of Key Signaling Pathways in Human Primed Pluripotency [RNA-Seq]
RNA-seq (gene expression) · human · 75 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 75 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- EIF3D safeguards the homeostasis of key signaling pathways in human primed pluripotencyScience advances · 2025
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE248702_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1045619 and SRA study SRP474607. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 75 more — browse all 75 samples with per-sample file links →
- GSE248820 EIF3D Safeguards the Homeostasis of Key Signaling Pathways in Human Primed Pluripotency 96 samples shares eif3d, pluripotency, homeostasis, safeguards, primed
- GSE309123 Poising and connectivity of emergent human developmental enhancers in the transition from naive to primed pluripotency - RNA-seq 9 samples shares pluripotency, rna-seq, primed
- GSE239860 HBV-driven host chromatin accessibility changes affect liver metabolic pathways, iron homeostasis and promote a preneoplastic phenotype [RNA-seq] 18 samples shares homeostasis, rna-seq
- GSE283597 LINE-1 transposable elements regulate the exit of human pluripotency and early brain development [bulkRNA-seq] 45 samples shares pluripotency, rna-seq
- GSE301297 Functional redundancy between UTY and UTX in regulating the localization of transcription factors involved in pluripotency [RNA-seq] 40 samples shares pluripotency, rna-seq
- GSE336167 RAI1 safeguards fidelity and tempo of human neurodevelopmental gene expression [RNA-seq] 36 samples shares safeguards, rna-seq
- GSE268535 Tracking and mitigating imprint erasure during induction of naïve human pluripotency at single-cell resolution [RNA-Seq] 32 samples shares pluripotency, rna-seq
- GSE274217 METTL3-dependent m6A RNA methylation represses transposable elements derived enhancers to suppress naïve pluripotency in human pluripotent stem cells [RNA-Seq] 28 samples shares pluripotency, rna-seq
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.