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RNA-seq analysis of gene expression regulated by LSD1 in CD8+ T cells

GSE248892 Mus musculus Expression profiling by high throughput sequencing 6 samples Submitted 2024/04/24 Platform GPL24247
Summary
In the RNA-seq analyses of in vitro activated and expanded CD8+ T cells, we found that GSK treatment significantly altered the transcriptome, with 241 genes upregulated and 426 genes downregulated respectively . Gene Ontology (GO) enrichment analysis revealed that the upregulated genes were highly enriched in biological processes related to cell killing and cytokine production.
Published in
Priming with LSD1 inhibitors promotes the persistence and antitumor effect of adoptively transferred T cells
Qiu F, Jiang P, Zhang G et al. · Nature communications 2024 · PMID 38773088 · doi:10.1038/s41467-024-48607-4
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Also filed as BioProject PRJNA1046395 and SRA study SRP474822. Searching any of these in the dataset finder brings you back here.

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